Research reference only. Research reference only. All compound descriptions are for educational and research purposes. Nothing here constitutes medical advice. Not intended for human use. Always consult a qualified healthcare professional.
What it is
KPV is a tripeptide C-terminal fragment of alpha-MSH (Lysine-Proline-Valine) that carries the anti-inflammatory activity of the parent hormone. Binds to melanocortin receptors (MC1R and MC3R) on immune cells, intestinal epithelial cells, and CNS cells to suppress NF-kB signalling (the master switch of inflammation), reduce IL-1beta and TNF-alpha production, and strengthen intestinal epithelial barrier function. Research applications include inflammatory bowel disease models, gut permeability research, skin inflammation, and systemic anti-inflammatory baseline support. In the KLOW blend it provides the gut-lining protection and immune-calming layer.
Reconstitution & Dosing
| Parameter | Value |
|---|---|
| BAC water | 3ml |
| Each injection | 10iu |
| mg per injection | 0.33mg |
| When | Daily. |
| Duration | 1-3 months |
MC1RMC3RNF-kBGutAnti-Inflammatory